Bulk N-Acetyl Cysteine Powder (NAC) Supplier with Factory China (2025)

What is N-Acetyl Cysteine?

N-Acetyl Cysteine powder (NAC), also known as N-Acetyl-L-Cysteine or Acetylcysteine (CAS Number: 616-91-1), is a semi-essential amino acid derivative and powerful antioxidant with the molecular formula C₅H₉NO₃S and a molecular weight of 163.19 g/mol. NAC is synthesized rather than botanically sourced, typically appearing as a white crystalline powder with a characteristic sulfur odor.

Wuxi Cima Science Co., Ltd., the leading bulk NAC powder supplier in China, offers pharmaceutical-grade NAC with 99% minimum purity verified by HPLC, featuring exceptional bioavailability in its free-form structure for maximum absorption and efficacy in the human body. Cima‘s premium NAC powder is available in various package sizes, including 1kg foil bags, 25kg drums, and custom packaging options to meet diverse client needs, and beyond supplying the raw ingredient, Wuxi Cima Science also provides comprehensive OEM services for finished NAC finished products including capsules, tablets, powders, and other dosage forms for global health supplement brands.

NAC Forms & Specifications

N-Acetyl-L-Cysteine (NAC) in its free form exists in a pure, unbound state rather than being attached to or combined with other compounds like salts or esters. This unmodified structure represents NAC in its most natural and potent state, making it highly desirable for health applications and supplement formulations.

Premium quality NAC produced by Cima Science maintains a minimum purity level of 99% as verified through HPLC (High-Performance Liquid Chromatography) testing. This exceptional purity standard ensures maximum effectiveness when used in health supplements.

N-Acetyl-Cysteine vs Glutathione

While both NAC and glutathione powder play crucial roles in antioxidant defense and detoxification, NAC generally offers superior practical benefits for most consumers. NAC serves as a precursor to glutathione in the body, effectively raising glutathione levels while being more stable, affordable, and bioavailable through oral supplementation. Glutathione, though powerful when it reaches cells, struggles with poor oral absorption unless in liposomal form. NAC demonstrates stronger clinical evidence for liver support, while glutathione may have slight advantages for skin whitening effects. Many health practitioners recommend taking NAC with vitamin C for optimized glutathione production rather than direct glutathione supplementation. The combined approach of NAC, glutathione, and vitamin C offers synergistic benefits for comprehensive antioxidant support, but NAC alone often provides the best value for enhancing glutathione status. Detailed Comparison of NAC vs Glutathione is as below:

FeatureN-Acetyl-Cysteine (NAC)Glutathione
CAS Number616-91-170-18-8
Other NamesAcetylcysteine, N-Acetyl-L-CysteineGSH, L-Glutathione, Reduced Glutathione
Molecular FormulaC₅H₉NO₃SC₁₀H₁₇N₃O₆S
Molecular Weight163.19 g/mol307.32 g/mol
AppearanceWhite crystalline powderWhite to off-white powder
Food SourcesNot directly found in foods (cysteine found in chicken, turkey, yogurt, eggs)Avocados, asparagus, spinach, okra, fresh fruits
Specifications99% by HPLC (Wuxi Cima Science standard)98-99% by HPLC for pharmaceutical grade
Oral BioavailabilityModerate to good (can cross cell membranes)Poor (easily degraded in GI tract) unless liposomal
PotencyModerate directly; high as glutathione precursorHigh when it reaches cells
Half-life5.6-6.25 hours2-3 hours in plasma
StabilityHighly stable in supplement formUnstable, easily oxidized, degrades quickly
PopularityVery high; widely used in clinical settingsGrowing, especially in liposomal and cosmetic applications
Pricing$30-60/kg bulk; $15-30 for consumer supplements$200-500/kg bulk; $30-80 for consumer supplements
Liver BenefitsStrong direct evidence for liver protectionBeneficial but less direct evidence than NAC
Skin WhiteningModerate effectsMore pronounced effects than NAC
Respiratory SupportExcellent (used medically as mucolytic)Moderate effects
DetoxificationExcellent, clinically used for acetaminophen overdoseExcellent but limited by bioavailability
Prescription StatusPreviously OTC in US, now more regulatedGenerally available as supplement
ManufacturingSynthesized (Wuxi Cima Science is a leading supplier)Synthesized or yeast-derived

Synergistic Applications:

  • NAC + Glutathione:NAC enhances glutathione production while providing direct benefits
  • NAC + Vitamin C:Vitamin C regenerates oxidized glutathione and enhances NAC efficacy
  • Liposomal Glutathione vs NAC:Liposomal delivery improves glutathione absorption but at significantly higher cost than NAC
  • Liver Support Protocol: NAC is often preferred over glutathione for direct liver protection
  • Skin Brightening:Combination of NAC, glutathione and vitamin C provides optimal results for skin tone improvement

Wuxi Cima Science offers premium NAC powder at 99% purity for manufacturers seeking to develop effective glutathione-boosting supplements, combination formulas, and OEM finished products.

N-Acetyl-L-Cysteine Manufacturing Process

Wuxi Cima Science employs a sophisticated, pharmaceutical-grade manufacturing process for N-Acetyl-L-Cysteine (NAC) production, adhering to strict GMP and ISO standards. The process begins with premium-quality L-cysteine that undergoes a controlled acetylation reaction under precise temperature and pH conditions. This is followed by multiple purification stages, including crystallization, filtration, and advanced chromatography techniques to eliminate impurities. Each batch undergoes rigorous quality control testing, including HPLC analysis to verify a minimum of 99% purity, heavy metal screening, and microbial testing. The final product is carefully dried using specialized low-temperature methods that preserve the molecular integrity of NAC while yielding a consistent white crystalline powder. Cima Science’s manufacturing facility features state-of-the-art equipment with automated monitoring systems throughout production, ensuring exceptional batch-to-batch consistency and full traceability from raw materials to finished products.

NAC Benefits

N-Acetyl Cysteine (NAC) is a remarkable supplement that functions as a direct antioxidant and a precursor to glutathione, the body’s master antioxidant. With decades of clinical research supporting its use, NAC offers diverse benefits ranging from respiratory health to cognitive function. Here are the key evidence-based benefits of this versatile compound:

  • Lung Health & Immune Support– NAC provides powerful nutritional support as an antioxidant, supporting lung functioning through its mucolytic capability
  • Respiratory Support Supplement– NAC N-Acetyl Cysteine supports lungs and their functioning through its mucolytic and antioxidant action
  • Powerful Antioxidant Protection– N-Acetyl Cysteine (NAC) is a precursor to the antioxidant glutathione; supplemental NAC supports tissue levels of glutathione
  • Liver Support & Detoxification– The supplement N Acetyl Cysteine supports liver health and detoxification; typically free from gluten, wheat, and common allergens
  • Immune System Enhancement– May reduce frequency and severity of certain viral infections
  • Brain Health Protection– Shows promise for conditions involving neuroinflammation and oxidative stress
  • Fertility Support– May improve sperm quality, motility, and overall reproductive health
  • Mood Regulation– Emerging research suggests benefits for certain mood and psychiatric disorders
  • Kidney Protection– Helps prevent damage from contrast dyes used in medical imaging
  • Skin Health Improvement– Supports clearer skin through antioxidant and anti-inflammatory properties
  • Heavy Metal Detoxification– Assists in binding and removing certain heavy metals from the body

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Where to buy N-Acetyl Cysteine Bulk Powder?

Wuxi Cima Science Co., Ltd. is China’s premier NAC factory, providing pharmaceutical-grade N-Acetyl Cysteine powder to global supplement brands, pharmaceutical companies, and distributors. Our state-of-the-art manufacturing facility operates under strict GMP certification, ensuring every batch of NAC meets 99% purity standards verified by HPLC testing.

Superior Quality, Competitive Pricing

As a direct bulk NAC supplier, we offer:

  • Highly competitive wholesale NAC powder pricing
  • Consistent batch-to-batch quality
  • Third-party testing documentation
  • Free samples for quality evaluation
  • Multiple certifications: GMP, ISO, Kosher, Halal
  • Custom packaging options from 1kg to 25kg drums

Complete OEM Services Available

Beyond raw ingredient supply, Wuxi Cima Science provides comprehensive OEM/ODM services for finished NAC products, including:

  • Capsules and tablets
  • Powder blends
  • Custom formulations
  • White label packaging
  • Regulatory documentation support
    Bulk N-Acetyl Cysteine Powder (NAC) Supplier with Factory China (2025)
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